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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NEK9
All Species:
20.61
Human Site:
Y845
Identified Species:
45.33
UniProt:
Q8TD19
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TD19
NP_149107.4
979
107168
Y845
S
E
K
D
T
L
P
Y
E
E
L
Q
G
L
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001097546
979
107204
Y845
S
E
K
D
T
L
P
Y
E
E
L
Q
G
L
K
Dog
Lupus familis
XP_547912
974
106819
Y841
S
E
K
D
T
L
P
Y
E
E
L
Q
G
L
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8K1R7
984
107065
Y852
S
E
K
D
T
L
P
Y
E
E
L
Q
G
L
K
Rat
Rattus norvegicus
NP_001100217
958
104862
Y844
S
E
K
D
T
L
P
Y
E
E
L
Q
G
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506669
536
57599
T423
A
E
C
N
K
P
T
T
E
A
W
P
P
R
L
Chicken
Gallus gallus
XP_001235085
1086
118657
Q952
E
K
E
T
L
P
Y
Q
E
L
Q
G
L
K
V
Frog
Xenopus laevis
Q7ZZC8
944
104521
D824
D
V
R
E
T
P
P
D
A
L
E
K
P
S
F
Zebra Danio
Brachydanio rerio
Q90XC2
697
76523
T584
T
A
H
S
V
A
V
T
E
K
G
Q
C
F
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781356
721
79856
G608
S
N
Q
Y
G
Q
L
G
V
G
D
C
K
G
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RXT4
555
62879
Q442
P
E
D
I
F
Q
N
Q
N
R
E
T
A
S
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.4
95.7
N.A.
95
93.6
N.A.
44.8
76
69.5
24.1
N.A.
N.A.
N.A.
N.A.
40.2
Protein Similarity:
100
N.A.
99.4
96.8
N.A.
96.4
95
N.A.
48.9
81.4
80.1
41
N.A.
N.A.
N.A.
N.A.
52.8
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
13.3
6.6
13.3
13.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
26.6
20
33.3
26.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
0
10
0
0
10
10
0
0
10
0
0
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
10
10
0
0
% C
% Asp:
10
0
10
46
0
0
0
10
0
0
10
0
0
0
0
% D
% Glu:
10
64
10
10
0
0
0
0
73
46
19
0
0
0
0
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
0
0
0
10
10
% F
% Gly:
0
0
0
0
10
0
0
10
0
10
10
10
46
10
0
% G
% His:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
46
0
10
0
0
0
0
10
0
10
10
10
46
% K
% Leu:
0
0
0
0
10
46
10
0
0
19
46
0
10
46
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
10
0
0
10
0
10
0
0
0
0
0
0
% N
% Pro:
10
0
0
0
0
28
55
0
0
0
0
10
19
0
0
% P
% Gln:
0
0
10
0
0
19
0
19
0
0
10
55
0
0
0
% Q
% Arg:
0
0
10
0
0
0
0
0
0
10
0
0
0
10
19
% R
% Ser:
55
0
0
10
0
0
0
0
0
0
0
0
0
19
0
% S
% Thr:
10
0
0
10
55
0
10
19
0
0
0
10
0
0
10
% T
% Val:
0
10
0
0
10
0
10
0
10
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
10
46
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _